Yes. You’ll need to swap out the egg whites (sub aquafaba or silken tofu for a similar texture) as well as the condensed milk and whipped topping. You can sub both of those ingredients with full fat coconut whipped cream, making this a cake that is easily made vegan.
Ingredients
1 package white cake mix (regular size)
3 large egg whites, room temperature
1-1/4 cups water
1/3 cup sweetened shredded coconut
1 can (14 ounces) fat-free sweetened condensed milk
1 teaspoon coconut extract
Directions
Preheat oven to 350°. Coat a 13x9-in. pan with cooking spray.
Beat cake mix, egg whites, water and coconut on low speed 30 seconds. Beat on medium 2 minutes. Transfer to prepared pan. Bake until a toothpick inserted in center comes out clean, 20-25 minutes. Cool on a wire rack 10 minutes.
Mix milk and extract. Using a large meat fork, poke holes in cake. Gently spread half of the milk mixture over cake; let stand 3 minutes. Spread with remaining milk mixture; cool 1 hour.
Spread with whipped topping; sprinkle with toasted coconut. Refrigerate, covered, until cold, about 4 hours.